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HomeNewsOrgan chip technology: reshaping the subversive breakthrough of the future of medicine

Organ chip technology: reshaping the subversive breakthrough of the future of medicine

Apr15
Gu Zhongze, who developed organ chips, developed simulated human organs through 3D printing and nano -processing technology in the high -molecular materials of the human environment. Among them, artificial vascular chips are used for the operation of Shenzhou -15 astronauts on orbit experiments, becoming the first international space station research on the research of artificial vascular tissue chips. Through the efforts of the past ten years, the team has continuously overcome technical problems, such as using static spinning technology to create extracellular brackets and developing high -precision printing institutions to create bionic blood vessels, etc., providing important support for the application of organ chips. In the market, organ chips have been used in the fields of disease modeling, drug screening, aerospace medicine and cosmetics evaluation, and provided new ideas and methods for drug research and development. Through cooperation with Hengrui Medicine, 9 batches of compounds have been selected on cardiac chips, which provides important support for new drug research and development, and shows the huge potential of organ chips in accelerating drug development and promoting the rapid development of biomedicine.

Event 1: Professor Gu Zhongze introduced organ chips
Professor Gu Zhongze held a organ chip and carefully introduced the background and application prospect of this technology to the reporter of the Science and Technology Daily. In his narrative, we learned that this technology uses polymer materials and advanced manufacturing technology, such as 3D printing and nano -processing, which can simulate the human environment in vitro, thereby cultivating organ tissues including the heart, liver and lungs. These simulated organ organizations can not only jump, metabolize and breathe in the laboratory, but also use related research on drug development and precision medical care. The prospect of this innovative technology is exciting and is expected to bring revolutionary changes to the field of medical research.

Incident 2: The application of artificial blood vessel chips in Shenzhou No. 15 space clerk experiments
The artificial vascular chip developed by Gu Zhongze's team has recently been applied to the experimental operation of Shenzhou No. 15stone. This is my country's first organ chip project implemented in the space station, and it is also the first international artificial vascular tissue chip research. Through this experiment, we learned that this technology not only made a breakthrough in ground experiments, but also successfully operated in space environment. This provides important technical support for further exploration and application in the field of aerospace medicine.

Event 3: Origin and development of organ chips
The origin of organs chip dates back to the beginning of the 21st century. At that time, the United States established a micro -physiological system alliance to start the research and development of organ chips. Professor Gu Zhongze accidentally came into contact with relevant research papers during his career "bottleneck period" and was attracted by the concepts, and began his research work. Although the technology was at the forefront at the time, Professor Gu Zhongze and his team still decided to conduct related research within the laboratory. After years of hard work, they gradually conquered the technical difficulties and achieved a series of important research results.

Event 4: technical breakthroughs to solve the problem of cell growth direction
During the research and development of organ chips, the team faces many technical challenges. One of the key issues is how to make cells grow more unified in the direction of in vitro to simulate the structure and function of the real organs. To solve this problem, Professor Gu Zhongze and his team used electrostatic spinning technology to successfully create an extracellular bracket material that can guide cells to grow in a specific direction. This technological breakthrough lays an important foundation for subsequent organ chip research and development.

Event 5: R & D of Bionic Vascular Technology
In addition to solving the problem of cell growth direction, the team also started to develop bionic vascular technology to realize the oxygen and nutrition of cells. They used high -precision printers to construct bionic blood vessels in organ chips, and control the penetration of nutrient solution through tiny pores, thereby achieving effective supply to cells. The successful research and development of this technology provides important technical support for the actual application of organ chips.

Incident 6: The application of organ chip in the field of pharmaceuticals
After years of research and development, organ chips have been widely used in the field of pharmaceuticals. For example, Gu Zhongze's team cooperated with Hengrui Medicine to use cardiac chips to screen drugs to provide important technical support for the development of new drugs. In addition, organ chips can also be used in the fields of disease modeling, drug screening, aerospace medicine and cosmetics evaluation, providing new ideas and methods for precision medicine and drug research and development.

Incident 7: Gu Zhongze's team established Jiangsu Ai Weiden Biotechnology Co., Ltd.
After achieving a series of important research results, Gu Zhongze's team established Jiangsu Ai Weiden Biotechnology Co., Ltd. to accelerate the industrialization process of organ chips and supporting automation systems. By cooperating with pharmaceutical companies, they successfully applied organ chips to clinical trials and provided important technical support for drug research and development. This measure not only promoted the transformation of technology and the development of the industry, but also laid a solid foundation for the rapid development of the biomedical field in my country.

Event 8: Gu Zhongze's team promotes the national standard plan
Gu Zhongze's team is leading the drafting of the National Standard Plan "Skin Chip Common Technical Requirements", which provides important support for the standardization of organ chips. This measure helps to standardize the production and application of organ chips, and improve its credibility and reliability in the medical field. By promoting the formulation of the national standard plan, Gu Zhongze's team further strengthened the leading and control of organ chip technology, and made positive contributions to the healthy development of the biomedical industry in my country.

Summarize:
The team led by Professor Gu Zhongze has successfully developed organ chip technology with important application value through years of efforts and innovation. This technology uses advanced technologies such as polymer materials, 3D printing and nano -processing. It can simulate the structure and function of human organs in vitro, providing new ideas and methods for drug development and precision medical care. By cooperating with pharmaceutical companies, Gu Zhongze's team has applied organ chips to clinical trials and has achieved a series of important research results. In the future, with the continuous improvement of technology and the gradual development of the industry, organ chip technology is expected to play a greater role in the field of medical research and make greater contributions to human health.


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